Buprenorphine is a potent, long-acting analgesic acting at opiate receptors in the central nervous system. The product should not be used pre-operatively in cases of Caesarean section, due to the risk of respiratory depression in the offspring periparturiently, and should only be used post-operatively with care. In case of an overdose, supportive measures should be instituted and if appropriate, naloxone may be used. Buprenorphine may cause respiratory depression and care should be taken when treating animals with impaired respiratory function or animals that are receiving drugs that can cause respiratory depression. The safety of buprenophine has not been established in breeding, pregnant or lactating cats. Subscribe to Drugs. Shake well before use. Buprenorphine undergoes N-dealkylation and glucuronide conjugation by the intestinal wall and the liver and its metabolites are excreted via the bile into the gastro-intestinal tract. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Vetergesic vet mg / ml solution for injection for dogs and cats (FI, HU, Repeat administration earlier than the recommended repeat interval.
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Vetergesic Multidose, mg/ml, Solution for Injection for Dogs and Cats. PuAR correct as of Ceva Animal Health Ltd. Unit 3 Anglo Office Park once, after hours.
The route of administration is intramuscular or intravenous injection. Vetergesic Multidose mg/ml Solution for Injection for Dogs, Cats Repeat administration earlier than the recommended repeat interval is.
Intramuscular injection. Combined pharmacokinetic and pharmacodynamic studies have demonstrated a marked hysteresis between plasma concentrations and analgesic effect. Post-operative analgesia in the cat.
Dog: 10 — 20 microgram per kg 0.
Although post-implantation losses and early foetal deaths were observed, these may have resulted from a lower level of parental care owing to sedation of the mothers.
Vetergesic administration office
|In these cases, consideration should be given to use of an analgesic from an alternative class.
As buprenorphine is metabolised by the liver, its intensity and duration of action may be affected in animals with impaired liver function. Therefore, the responses of individual animals should be monitored and subsequent doses should be adjusted accordingly.
Loading image navigation It is generally recognized that this method of reporting results in significant underreporting of adverse drug reactions.
To ensure that analgesia is present during surgery and immediately on recovery, Vetergesic Multidose should be administered pre-operatively as part of. sation for administration to cats and can be administered by intramuscular (IM) Buprenorphine without a preservative (Vetergesic. Injection; Alstoe) (BUP) has been This study was performed under Home Office Licence.
Solutions showing haziness, particulate matter, precipitate, discolouration and leakage should not be used.
Viewing Datasheet Vetergesic 0. At clinical dose levels for analgesia, buprenorphine binds to opiate receptors with high affinity and high receptor avidity, such that its disassociation from the receptor is slow, as demonstrated in in vitro studies. Following intramuscular injection in cats, the mean terminal half-life was 6. If additional analgesia is subsequently required, this may be achieved by administration of a further dose of Vetergesic or concomitant use of a suitable injectable NSAID.
However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.
Vetergesic Multidose (Canada) for Animal Use
Ceva Animal Health Ltd.
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|Keyword s :. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. In cases of overdosage, supportive measures should be instituted, and, if appropriate, naloxone or respiratory stimulants may be used.
Search in datasheet. Please wait a moment while we find what you are looking for…. The safety of buprenorphine has not been established in cats less than 7 weeks of age.