Efavirenz: A. The compounds of the invention are also suitable for the treatment of viral diseases, such as infections caused by papilloma viruses, herpes viruses, Epstein-Barr virus, hepatitis B or C viruses and human immunodeficiency viruses. For intra-articular injection, correspondingly prepared crystal suspensions can be used. The activity represents a good measurement of the undesirable catabolic effects of glucocorticoids. Compounds of general formula I in which R 4 is methyl are preferred. After removal of the solvent gave 20 mg of the desired product as a solid. Herzton evtl. Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension.
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Struma, Haarausfall, Morbus Basedow, Kallmann-Syndrom, Osteoporose, Lada, Phochromozytom, Angeborene Hypothyreose, Adrenogenitales Syndrom. auf folgende Nebenwirkungen zu achten: Cushing-Syndrom mit.»Mondgesicht« und es sich entweder um ein adrenogenitales Syndrom oder um . Kaiser, E.: Antiandrogene Behandlung bei Akne, Haarausfall und Hir- sutismus.
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Münch. Aurikulotemporales Syndrom Auspitz-Phänomen Adrenogenitales Syndrom Adson-Test Akantholyse. Haarausfall - kreisrunder
Darstellung der linken Koronararterie mittels Herzkatheter. Benzo[1,3]dioxolyl -cyclobutyl-carbonitril Benzo [1,3] dioxolyl -cyclobutyl-carbonitrile. DEC2 en.
DEA1 Substitulerte 3,4dihydroquinoxalin2 (1H) one Google Patents
Carboxylic acids of general formula II the radicals R4 to R8 have the meanings defined in formula I are converted to known to those skilled methods under basic or acidic conditions with a corresponding alkyl halide or with a corresponding alcohol to the corresponding ester with R9. AngiographieAortographie.
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Usually enantiomers of the invention varies greatly inhibit the target proteins and are different active in the tested cancer cell lines. When R 4 and R 5 form a common ring, then, particularly preferred are the 1,3-dioxole, furanyl, dihydrofuranyl and 1,3-Oxazolringsysteme.
R 7 and R 8 is connected to carbon atom of the 4- to 8-membered heterocycloalkyl, are each independently hydrogen or C 1 -C 4 alkyl, or R 7 and R 8 together with the nitrogen atom to which they are attached represent 4- stand to 8-membered heterocycloalkyl, which is optionally mono- or may be disubstituted by identical or different substituents selected from halogen or C 1 -C 3 alkyl, R 9 is hydrogen, R 10 is C 1 -C 4 alkylR 11 is C 1 -C 4 alkyl, as well as the diastereomers, racemates, polymorphs and physiologically acceptable salts thereof.
The following examples illustrate the preparation without limiting the invention to these examples of the inventive compounds.
DEA1 NSAIDs Google Patents
32. Mukoviszidose. GlucosePhosphat- Dehydrogenase. Haare: brüchig, Haarausfall, Reißlast↓.
. Kardiovaskulär: Endogenes Cushing-Syndrom → selten Hautblutungen, Hautinfektionen, Akne, Haarausfall.
Freisetzung von Ammonium aus Glutamin. In the C 3 -C 6 cycloalkyl group is, for example, a monocyclic hydrocarbon ring such. Combinations with anti-hormones and steroidal metabolic enzyme inhibitors are particularly suitable because of their favorable side effect profile.
The anti-inflammatory activity of the compounds of the general formula I were tested in the animal experiment in the croton oil-induced inflammation in the mouse and in the rat J. Bei der C 3 -C 6 -Cycloalkylgruppe handelt es sich zum Beispiel um einen monocyclischen Kohlenwasserstoffring, z. The term "isotopic variant" of a compound or reagent is defined as a compound with an unnatural amount of one or more of the isotope, from which such a connection is established.
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